Monday, December 29, 2014

The Effects of Diabetes Drug on Liver

The effects of diabetes drug on liverDiabetes drug works to lower blood sugar levels of diabetics by reducing the uptake of glucose from the liver. it aims to lower blood glucose levels in order to be close to normal.but the effects are actually sufferers often experience hypoglycemia. Then like what the mechanism of diabetes drugs in lowering blood glucose levels, especially for the liver?
the effect of diabetic drug
the effect of diabetic drug

Normal liver healthy person would produce glucose when eaten with the aim of stabilizing blood glucose levels. when blood glucose levels stable, it will produce enough energy to perform daily activities. meanwhile, when food enters the body, insulin is secreted by the beta cells of the pancreas, whereas glucose production from the liver is reduced. This process causes the blood glucose stability is maintained properly.

in contrast to patients with type 2 diabetes, which when insulin secretion by pancreatic beta cells do, hepatic glucose production will still take place. This condition is called insulin resistance, which is causing a spike in blood sugar. so when diabetes drugs stimulate glucose production in the liver in order to diminish, the goal is to keep blood glucose levels. Although effective in such matters, lowering blood glucose, how drugs work like this is not going to solve the problems existing diabetes, insulin-resistant infections is precisely the one that must be addressed.

The effects of diabetes drugs work against Liver
In general, there are 6 types of medications for diabetes, where 3 of them work to lower blood sugar by increasing insulin secretion. While 3 other drug works to lower blood sugar by reducing the uptake and glucose production in the liver. The following 3 drugs in question:

Biguanide
the workings of this type of drug in treating diabetes is by stopping the production of glucose in the liver and increases the ability of insulin to process glucose absorption back into the cell. Although effective in lowering blood sugar of diabetics, this type of drug can increase the risk of hypoglycemia. In addition, diabetic patients with liver disorders, drug types biguanide lactic acidosis, which can trigger the patient's blood becomes more acidic.

DPP-IV Inhibitors
This type of drug the way it works is similar to the type of biguanide. How it works kind of DPP-IV drug inhibitors would also stimulate the liver to stop the production of glucose in excessive amounts, so that the blood glucose levels can be re-approached the stable.

Thiazolidinedione
These drugs work to lower blood sugar by reducing glucose production in the liver and increase the effectiveness of insulin in the process of absorption of glucose into the cell.

The Effects of Diabetes Drug on Liver 

The most dangerous side effects are side effects that arise after the use of a thiazolidinedione type of diabetes medication. Considered the most dangerous because it is often the drug of this type can increase the levels of enzymes in the liver. Plus it can be the disruption of the more severe liver, although it is rarely found in people with diabetesTherefore, the use of the drug is recommended to perform the type of thiazolidinedione regular blood tests in order to avoid interference or even liver damage.

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